Antibody Panels and Kits
Biotium Bcl-6 (Follicular Lymphoma Marker) (BCL6/1718), CF488A conjugate, 0.1mg/mL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Enzo Life Sciences AMPIGENE DNA Ladder 100-1,500 bp (100lanes)
AMPIGENE DNA Ladder 100-1,500 bp contains DNA fragments ranging from 100bp to 1,500bp that can be used as molecular weight standards for agarose gel electrophoresis. The bands are evenly spaced and are intensified at 500bp and 1,500bp to serve as easily identifiable reference bands. The approximate mass of DNA in each of the bands is provided, assuming 5µl load, for determining the approximate mass of DNA in samples with comparable intensity and size. Long Term Storage: -20°C.
Biotium Bcl-6 (Follicular Lymphoma Marker) (BCL6/1718), CF568 conjugate, 0.1mg/mL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Cell Signaling Technology PhosphoPlus(R) RIP3 (Thr231/Ser232) Antibody Duet 1 Kit
PhosphoPlus(R) RIP3 (Thr231/Ser232) Antibody Duet 1 Kit
Cell Signaling Technology Rag and LAMTOR Antibody Sampler Kit 1 Kit
Rag and LAMTOR Antibody Sampler Kit 1 Kit
Cell Signaling Technology Lysine Acetyltransferase Antibody Sampler Kit 1 Kit
Lysine Acetyltransferase Antibody Sampler Kit 1 Kit
Cell Signaling Technology Wnt/beta-Catenin Activated Targets Antibody Sampler Kit 1 Kit
Wnt/beta-Catenin Activated Targets Antibody Sampler Kit 1 Kit
Cell Signaling Technology PhosphoPlus(R) MLKL (Ser358) Antibody Duet 1 Kit
PhosphoPlus(R) MLKL (Ser358) Antibody Duet 1 Kit
Cell Signaling Technology Phospho-TSC2 Antibody Sampler Kit 1 Kit
Phospho-TSC2 Antibody Sampler Kit 1 Kit
Vector Laboratories Lectin Kit II, Biotinylated
Our lectin screening kits are designed to provide the investigator with a panel of six lectins or lectin conjugates. The lectins have been selected to offer a variety of sugar specificities and are of the same high quality as the reagents offered individually.Each Kit II (LK-3000, BK-2100, FLK-3100, RLK-3200) consists of 1 mg of the following lectins or lectin conjugates: GSL I, LCA, PHA-E, PHA-L, PSA, Succinylated WGA.
Cell Signaling Technology Src Family Antibody Sampler Kit 1 Kit
Src Family Antibody Sampler Kit 1 Kit
Abcam CD8 alpha Antibody Panel (SP16, CAL67, CAL66, EPR22483-288, EPR10640(2))
CD8 alpha Antibody Panel (SP16, CAL67, CAL66, EPR22483-288, EPR10640(2))
The product is subject to the following: Abcam Restricted Use Statement
Cell Signaling Technology Cellular Localization IF Antib
Cellular Localization IF Antibody Sampler Kit 1 Kit
Biotium HIF1 alpha (Hypoxia-Inducible Factor 1-alpha)(ESEE122), CF568 conjugate, 0.1mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc. ) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains sta